Sentence examples for most strongly selected from inspiring English sources

We can understand this result from the fact that the timescale of population-size fluctuations is so fast that all but the most strongly selected alleles still fall within the weak selection limit, described by the harmonic mean effective population size.

In this interpretation, genes with lowest noise have been most strongly selected against noise, whereas high noise genes have experienced much weaker selection against noise.

Because many scans for selection involve comparisons of divergence between "pairs" of species (usually in the form of the ratio of nonsynonymous to synonymous substitutions), they cannot polarize evolutionary change along individual lineages nor can they distinguish between positive selection and a relaxation of constraint for any but the most strongly selected genes.

Inter-population FST and Thoroughbred Ho was plotted across chromosomes containing the nine most strongly selected loci (Figure 3).

Our result then suggests that only the most strongly selected alleles, which can arise and sweep over a single season, may actually fall within the strong selection limit.

Two quantitative trait loci of large effect were not the most strongly selected of the loci due to their antagonistic pleiotropic effects on strongly selected phenotypes.

It is clear from Figure 3 that this is the CpG motif that the H1N1 virus has been most strongly selecting against.

However, as the founder epitopes were replaced by mutational variants, the initial CTL responses immediately declined, most early and rapidly in strongly selected epitopes.

As CTL epitopes were replaced by mutational variants, the corresponding responses immediately declined, most rapidly in the cases of strongly selected epitopes.

Risk of aspiration pneumonia (the most common cause of death in SBMA patients; Katsuno et al. 2010), muscle degeneration, and loss of mobility would likely have been strongly selected against under most ancestral conditions.

We conclude that, despite historical differences in N e for the two species, most newly arising nonsynonymous mutations are sufficiently strongly selected that these differences have played little role in the dynamics of protein evolution.