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The most stringent approach to identify positive selection compares the M1a null model, which has two values of ω (ω <1, ω =1), and M2a, which has an additional third category of ω that is greater than one.
As we had three study groups (infertile ART, donor oocyte ART, and fertile control, see ' Methods'), the most stringent approach to determine whether differences exist is ANOVA followed by Tukey's post hoc HSD test to identify which specific groups are responsible for any significant differences.
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Australia is considered to have the most stringent regulatory approach to EDs internationally.
This can be done in several ways, ranging from very stringent approaches to very relaxed ones; from the most to the least stringent approach, one counts the hierarchy of elements (graph-cluster contrast), parts of the hierarchy (relaxed-graph-cluster contrast), only the elements devoid of hierarchy (set-cluster contrast) and parts of the elements (relaxed-set-cluster contrast).
The validation of our T1D models on a different population provides the most stringent test of our approach.
Although this stringent approach is most likely an unrealistic representation of transcriptome variation, any continued differences observed in transcript abundance between GC and KN datasets should bolster support for our previous protein count results.
Only a small proportion of participants in the most stringent blood pressure group achieved this target despite the intensive approach with three or more drugs applied in the intervention.
Such an approach was defined as primary because it was deemed in line with the requirements of the most stringent regulatory authorities.
"Best" efforts is the most stringent standard.
"We abide by the most stringent rules," he said.
Media companies have taken the most stringent steps so far.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com