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The most straightforward candidate sites to test are the type-II sites and those subject to positive selection, where it is possible to change the relevant residue either to the amino acid present in the other group (for type-II sites) or the ancestral amino acid (for positively selected sites).
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The most straightforward challenges were disorders with an obvious candidate gene.
But Japan, which has looked like a secular stagnation economy for two decades suddenly seems less a candidate, and not because of any remarkable structural shifts in the economy.The most straightforward story for a place like America is that various factors, from inequality to foreign reserve accumulation to demand for safe assets, have depressed nominal interest rates in America.
The most straightforward way to search for signals of selection is to compare patterns of genetic variation at candidate loci to theoretical expectations from a neutral model of population history not involving selection.
For some candidates seen in only one technology, increasing sequencing depth may be the most straightforward solution to the lack of resolution for low abundance transcripts.
The first and most straightforward is geographic.
Anniversaries provide the most straightforward narrative peg.
This is the most straightforward approach.
Northwest is among the most straightforward.
"He's probably the most straightforward C.E.O.
And the most straightforward case occurs with the nonregulated tenant.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com