Thus far, the most standardised protein arrays make use of spotted antibodies (Borrebaeck and Wingren 2007).
DDP Full-Basic is the most standardised model of DDP and is the most compatible with the original USA based model [ 18, 34].
Most standardised assessments have relatively few physical function items (for example, the Health Assessment Questionnaire (HAQ) [ 1] and Arthritis Impact Measurement Scales 2 (AIMS2) [ 2]).
Of the three provinces, the Free State had the most standardised approach, the so-called "3x1 patient-walk-through" model, where patients moved between one of three "assessment" sites and a "treatment" site at particular points in the care pathway.
The most standardised methods for quantitative MS-based proteomics are based on selective labelling of proteins or peptides with stable isotopes, e.g. H, C, N or O. Nowadays, there are several choices for MS-based quantification in proteomics, and for this reason, only a few examples will be given in this review.
As another example, when ISH and RT PCR (two different techniques assessing RNA) studies were aggregated together, the heterogeneity increased (P=0.03) as compared with ISH alone (P=0.18) or RT PCR alone (P=0.1), and with only a few studies, the results were statistically significant for the RT PCR subgroup, which is the most standardised technique.
A standardised analytical approach was used to minimise the possibility of differential bias across participating cohorts.
The use of a standardised analytical protocol further increases reliability of the findings.
Future studies may consider a standardised analytical approach to gait analysis that will provide clinicians and researchers with objective evidence of foot function in people with IA.
In common with other papers in this series, we evaluated interventions for two major global regions using a standardised analytical approach.
