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In most sporadic forms of human cancers, promoter hypermethylation is responsible for hMLH1 gene inactivation.
Known as one of the Liberty's consistent players, she had had the most sporadic season of her career and thought maybe it was time to quit.
To be clear, this was in no way due to a lack of interest in the continent on my part, but rather because the news business itself accorded such little attention to Africa, and when it bothered to it tended to cover it in only the most sporadic and stilted ways, as if Africans were as impossible to grasp as extraterrestrials.
Most sporadic desmoids carry somatic mutations in CTNNB1.
Most sporadic CRCs with MSI-H are known to be associated with the methylation of the hMLH1 promoter.
Gastrointestinal and genitourinary cancers are the most common internal malignancies, with colorectal cancers often occurring at or proximal to the splenic flexure, contrary to most sporadic colorectal cancers.
Loss of function in the von Hippel-Lindau (VHL) tumor suppressor gene occurs in familial and most sporadic renal cell carcinomas (RCCs).
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Most are sporadic, but some are dominantly inherited.
Craniosynostosis is twice as frequent in males than in females and is most often sporadic, although the defect may be familial.
Most human sporadic colon cancers develop gradually as accumulating alterations in gene expression transform normal colonic epithelium to adenocarcinoma.
These patients do not fulfill any criteria indicative of HNPCC are thus most likely sporadic.
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CEO of Professional Science Editing for Scientists @ prosciediting.com