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The longest windows probably find the most specific haplotypes, which also can be seen in the scores.
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Therefore, despite changing the specific haplotypes used in randomly initializing the adapted PAM algorithm, most haplotypes eventually chosen for inclusion in the minimum-ADCL panel remain the same.
Hence, to study specific haplotypes, it was decided that a polymerase chain reaction (PCR -based aPCR -baseds most approachate, wasre single mostcules would represent pertinent regions of eappropriatepe.
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The effect of HPCX1 was proven to be the most important in the Finnish population, where a specific haplotype in the region was also identified [ 5, 6].
Thus, having a specific microsatellite means having a specific haplotype.
For both specific haplotype marker tests and the general comparison of haplotype frequencies by haplotype block, haplotype frequencies and subject-specific expected haplotype indicators were calculated separately for each study using the programme TagSNPs [24].
The development of ethnically tailored therapies, however, appears irrelevant in the case of the NAT2 gene polymorphism since (1) there were only few region-specific haplotypes and (2) most genetic diversity occurred between individuals rather than between populations.
However, given the presence of Mangalica-specific haplotypes, the isolation theory is the most likely.
Most Mangalica individuals belonged either to one of these common continental European haplotypes or to two Mangalica-specific haplotypes that were absent in all other breeds.
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