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At the same time, it will increase the accuracy of the approach as the overall vd and vi values will be based on a larger number of analyses as will be the case in most single validation studies.
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However, there has not been agreement on a single validation method most appropriate for global mental health research with adults or children.
Early phase validation testing may include a single validation run due to time constraints and limited availability of API.
The most rigorous validation is external validation, i.e., validation performed in an independent data set.
This is the most rigorous validation protocol.
The default validation type was "compounds out", i.e., the most rigorous validation protocol.
Most available validation tools have their own limitations.
The most important validation parameter is the detection capability (CCβ).
Most validation to date is at the level of numerical validation of the accuracy of simulation rather than experimental validation of the overall model [80].
While most validation studies have replicated the original single factor structure [ 7, 9], other studies found a better fit of the data with a two factor solution [ 10, 11].
The most elegant validations of pooling have used indirect approaches, such as spiking a single individual of known genotype into a pooled group with unkown genotypes [ 9].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com