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Artefactual or technical variability as a cause of differences in gene expression between samples was also excluded by the finding that the samples that shared the most similar technical processes (Mono+ and MonoD) had the most different gene expression, whilst those that underwent the most different processes (Mono+ and Mono−) had the most similar expression.
In order to gain insight into the mechanism of how cohesin is recruited to the ESC transcription factor binding sites, we performed a proteomic study on Nanog, the transcription factor with the highest enrichment score and the most similar expression pattern changes upon RAD21 depletion.
The most similar expression patterns were obtained from ap1 and wild type inflorescences.
Among these, wnt-5 exhibits the most similar expression pattern to fz-2 during somitogenesis.
The most similar expression profiles are joined together to form a group.
Then additional genes that have the most similar expression profiles to the query genes are identified in the datasets.
Similar(36)
Despite the substantial gene expression differences, ap1 revealed the most similar inflorescence expression pattern to sup ap1 in the library relative analysis (p < 0.001).
Clustering of tissues by only their overall gene expression patterns suggested that floral tissues, the bud samples, and root and xylem had the most similar gene expression profiles (Additional file 13).
We previously analyzed the gene expression pattern of blastemal, stromal and epithelial components of WT separately and showed that blastema displays the most similar gene expression pattern of the initial stages of nephrogenesis, and that the Wnt signaling pathway is supposedly involved in the earliest events of WT onset.
Autumn mothers and dwarf eldest daughters had the most similar transcript expression profiles (77% bootstrap support; Figure 3).
The forty disease categories having the most similar gene expression to that found in bladder biopsies of ulcerative IC patients are summarized in Table 5.
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