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The most significantly associated SNP from the linkage disequilibrium (LD) region is rs7849014.
most significantly associated with a poor prognosis (Fig. 9a).
Among these, the modules "Turquoise" and "Gray" were most significantly associated with a docetaxel-resistant status.
The computationally measured epithelial and/or stromal features most significantly associated with survival were then reviewed manually by human researchers.
We found that the Turquoise and Gray modules were most significantly associated with docetaxel-resistant status (Fig. 3B).
Of these variants, single SNP analysis revealed that CFH rs572515 was the most significantly associated with AMD risk (P < 10^-6).
Replication of the most significantly associated polymorphisms in multiple populations with distinctive genetic backgrounds and lifestyles is crucial to the understanding of the pathophysiology of a multifactorial disease like CAD.
Study design was the variable most significantly associated with subsequent publication (X2 = 12.2, p = 0.002).
Ferritin light chain (FTL) gene was the most significantly associated promoter revealing DNA hypomethylation in MS patients compared to controls.
When the high-risk factors were analyzed separately, Gleason score 8-10 was most significantly associated with increased PCSM (AHR 6.2; 95% CI, 3.5-11.2; p < 0.001).
The most significantly associated SNPs (P < 0.005) in this pedigree were rs4845663, rs7532286, rs6426929 and rs1218551, with the minor allele in each case conferring protection against migraine risk.
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