Sentence examples for most significant side from inspiring English sources

There was good tolerability, with cutaneous toxicity as the most significant side effect.

The most significant side effects of this group of compounds include weight gain, hepatotoxicity and cardiovascular manifestations.

The kinetic parameters for the ester interchange reaction, for the water formation through esterification as well as for the most significant side reactions were taken from the literature.

Zhang notes that the most significant side effect of these new drugs is diarrhea, which is experienced by less than 30% of patients.

Cytokine release syndrome, correlating with the in vivo activation and expansion of T cells, and neurologic toxicity are the most significant side effects and approaches to better understand and manage these events are the subject of ongoing clinical trials.

Myelosuppression was the primary and most significant side effect and was seen in most of the patients, varying in degree from mild to moderate.

One of the most significant side-effects associated with ECT is retrograde amnesia.

The most significant reported side effects of the combined regimen included hypertension, proteinuria, diarrhoea, and acne-like rash (Hainsworth et al, 2005).

Furthermore, there are studies showing that glucocorticoids may alter vascular function, and hypertension was shown to be the most significant negative side effect of chronic glucocorticoid treatment in humans [ 46, 47].

The most common significant side effects were: tiredness 31.3 %, sleepiness 18.2 %, memory problems 22.7 %, disturbed sleep 14.1 %, difficulty concentrating and unsteadiness 11.6 %.

Paclitaxel, an antimitotic agent derived from bark of Pacific Yew tree Taxus brevifolia (Schiff et al, 1979), proved to be active in relapsed and platinum-resistant ovarian cancer (McGuire et al, 1989; Einzig et al, 1992; Trimble et al, 1993; Kohn et al, 1994; Gore et al, 1995) and was well tolerated by most patients: significant side effects other than alopecia were uncommon (Seidman et al, 1996).