Sentence examples for most significant shift from inspiring English sources

The most significant shift in the metal content of American coins occurred in 1965.

The Conservative leader described it as the "most significant shift in power from the state to working people since the sale of council houses in the 1980s".

Many women's health experts say that the most significant shift of gears came at a 1994 conference in Cairo, which Dr. Sadik directed.

The most significant shift, Lawless added, has been among married women – a demographic that favors Republicans and chose Romney over Obama by seven percentage points in 2012.

The most significant shift we've made is requiring every final candidate to work with us for three to eight weeks on a contract basis.

The most significant shift in investor thinking is likely to focus on economic data, which Mr. Bernanke said was the primary factor driving the Fed's decision-making.

Analysts briefed on the work called it one of the most significant shifts in silicon transistor design since the integrated circuit was invented in the 1950s.

Alfredo's trip followed one of the most significant shifts in U.S. border policy in decades: the implementation of a strategy known as "deterrence through prevention".

That takes me to what I see as the most significant shifts in political discourse, which are really tonal rather than lexical.

The nonstop interactivity is one of the most significant shifts ever in the human environment, said Adam Gazzaley, a neuroscientist at the University of California, San Francisco.

The fact that the agency is in effect running a war in Pakistan is the culmination of one of the most significant shifts in the C.I.A.'s history.