Economic factors may have played the most significant role in his retirement.
Indeed, geography appears to play the most significant role in deciding Connecticut residents' loyalties.
But perhaps Mr. Hunger's most significant role is as Mr. Gore's fun-loving alter ego.
And that is where I think Mexico can play its most significant role".
The most significant role in the House of Representatives is that of speaker of the House.
Perhaps the most significant role Gertrude played was in convincing her cousin that her boyfriend was not going to win the war.
Reportedly the highest paid player in Scottish football, the midfielder's most significant role here was posing for photographs with children before kick-off.
Throughout the year, if you look at any British success stories – London Grammar, Rudimental, Disclosure, Bastille – Radio 1 has played the most significant role in breaking them.
Collins's other most significant role came in 1982's Who Dares Wins, when he played a member of the SAS.
"But how he handled himself in the most significant role he's had in public life, where he was given responsibility and authority, and whether or not he abused it, is a legitimate question".
In the language of weaving, however, the most significant role was to communicate with the spiritual world, the dead believed to be mediators between the living and the deities.
