By the common upstream search, KeyMolnet identified cAMP-response element-binding protein (CREB) as the principal transcription factor exhibiting the most significant relevance to molecular networks of both ADGs and IADGs.
The generated network, compared side by side with human canonical networks of the KeyMolnet library, composed of 430 pathways, 885 diseases, and 208 pathological events, enabled us to identify the canonical network with the most significant relevance to the extracted network.
In many pattern recognition applications, feature selection focuses on identifying the most significant features that have relevance to the interpretation of the target classes.
Analysis of the annotation of the most significant genes revealed the relevance of critical genes and pathways during bladder cancer progression (Sanchez-Carbayo et al, 2003b).
The most significant washcoat elements of catalytic relevance were Pt, Pd, Rh, Ba, Ce, Zr, Mg, Al, and these were present mainly in four distinct domains: (i) Mg/Al mixed oxide with Pt, Ce; (ii) Al oxide with Rh, Pd; (iii) Ce/Zr mixed oxide with Pt, Pd, Ba (high Ba content); (iv) Ce/Zr mixed oxide with Pt, Pd, Ba (low Ba content).
Analysis using a multivariate proportional hazard model identified the most significant RTKs that represented independent prognostic relevance.
This is of particular relevance since the most significant phenotypes we observed were restricted to the pharyngeal arch cartilage, arch vasculature and heart.
Instead, DIT testing should be required in the safety assessment of chemicals and drugs and should use end points of direct relevance to the most significant immune-based human diseases.
List activities on your resume according to relevance and significance for the job: most significant on top, and least significant near the bottom.
In this paper, we review the most significant issues in IAC coding and their relevance for future codec designs.
Frailty remains the most significant risk factor for falls, and its relevance is due to several factors including malnutrition, which is common in uremia.
