Sentence examples for most significant regulator from inspiring English sources

Hap4, a global regulator of respiratory genes, is the most significant regulator for this module and indeed 25 of its genes are known Hap4 targets.

LeMoNe infers for each module the most significant regulators, resulting in opposite characteristics of the degree distributions.

Of particular interest was the accurate prediction of CDK8 as the second-most significant regulator, recently identified as a colorectal cancer oncogene that regulates beta-catenin activity [ 38].

CD40 and several proinflammatory cytokines e.g. IL-1b, TNFa and IL-8 were up-regulated in our dataset, and CD154 was predicted as the most significant upstream regulator (Table  5, Figure  4).

The securities commission, which is Canada's most significant market regulator, initially on Friday ordered Mr. Chan and four other Sino-Forest employees to resign.

Bone morphogenetic protein 4 was the most significant upstream regulator (P overlap  = 1.99 × 10−6).

YEATS2 was predicted to be the most significant negative regulator shared by most of the metabolic pathways (Table 1).

In silico pathway analysis predicted that ATF4 was the most significant upstream regulator orchestrating pathological processes after ONC.

Peptidoglycan was identified as the most significant upstream regulator for the List eQG (Table  5, Figure  4).

IPA analysis identified the transforming growth factor (TGF β pathway as the most significant upstream regulator of the transcriptional network in preM ER+ breast cancer (Additional file 6).

From our already quoted investigations [ 15, 16], it follows that the concentration of HA also determines, essentially, the solubility of CaOX and that this substance may be the third and even most significant biological regulator of CaOX supersaturation in human urine.