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The most significant protein loss was observed for lubricated glass syringes.
Furthermore, the most significant protein interactions in the data suggested that DNA-repair complexes are activated by EWS-FLI1.
PARP1, represented by at least 31 distinct peptides, was the most significant protein identified by LC-MS/MS (Tables 1 2).
These are the most significant protein interactions found for upregulated genes, and the most significant annotation of this group is "DNA-repair" and "response to DNA damage stimulus".
As in UProC short read mode, only the most significant protein hit on a read was evaluated.
Table 7 shows the contingency tables for day five and 19 for true disease status and classification based on serum protein profiling using 50 most significant protein peaks.
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One of the most significant proteins associated with many lipid related diseases is APOB-100 (p = 0.01 to 0.005).
Several of the most significant proteins identified that increased in metastasis were those involved in the aerobic glycolysis pathway in cancer cells (Warburg effect).
Figure 4 shows representative plots of protein intensities of the four most significant proteins are shown: PKM2 (q value = 0.003), GLUT1 (q = 0.007), HSP90AA2 (q =��0.008) and L-lactate dehydrogenase B chain (LDHB, q = 0.008) in individual samples of primary and metastatic melanomas.
From this, we separately identified the 10 most significant proteins in early and late stage bladder cancer (Table 3).
As the most significant proteins in secondary infection were involved in the inhibition of apoptosis, the apoptotic process might an important mechanism in the zebrafish immune response against C. albicans, particularly during primary infection.
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