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We selected genes from the two most significant profiles, namely profiles 9 and 16, to construct a co-expression network.
Of these, four patterns were most significant (profiles 4, 7, 8, and 13, p < 0.00001, Figure 4A), and the enriched GO terms most significantly associated with these patterns are shown in Figure 4B.
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Among 22 expression profiles, the two most significant patterns (profiles No. 2 and No. 76) according to their P-values had the largest number of differentially expressed genes, including 239 and 245 genes, respectively.
Two of the most statistically significant profiles had complementary patterns (clusters labeled 1 and 6).
I am proud of the comprehensive nature of our efforts - not only with regard to random testing, groundbreaking blood testing for human Growth Hormone and one of the most significant longitudinal profiling programs in the world, but also our investigative capabilities, which proved vital to the Biogenesis case.
As this strain has the most significant resistance profile of the study, special attention was paid to the description of this efflux pump, which may have a role in resistance to antibiotics in place of SmeABC.
Among these patterns, the two most significant patterns were profiles No. 9 and No.16 according to ascending p-values.
"Goel substantially helped the Government secure a conviction in one the most significant and high-profile insider trading trials in history," the letter said.
The most significant tissue expression profile is epithelium.
The gene with the most significant endothelial specific profile was the metallo-proteinase gene MMP1, a surprising result as literature suggests this gene is widely expressed [ 27, 28].
The two functional categories that showed the most significant enrichment for profile 1 genes (Fig. S3) were 'control of cellular movement' and 'cell-to-cell signalling', and there was also an enrichment of genes associated with inflammation in this profile.
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CEO of Professional Science Editing for Scientists @ prosciediting.com