The most significant biological processes associated with cold-adaptation were translation, glycolysis, RNA processing, actin filament-based processes, and mRNA metabolic processes.
Though grain production is Skåne's most significant industry, food processing, shipbuilding, metalworking, manufacturing, stone quarrying, and fishing also are important.
The "-omics" era has brought with it numerous challenges and hurdles, the most significant being the processing of the massive amount of datasets and the extraction of biological meaning from them [ 3].
Food processing is one of the most significant types of the processing industries in the region, supporting agricultural production in the area and encompassing meat packing, fruit and vegetable processing, sugar refining, confectionery and dairy industry.
Although this definition fits the use of extrusion in the production of pasta, the most significant applications in food processing are in the area of extrusion cooking.
In the discussion below, we consider in further detail, the most significant features of chemosensory processing in the MeA that emerged from our study.
In the pathway analysis, 15 significant pathways were identified when we mapped the DE genes to the KEGG database (see supplementary Table 4), and the three most significant pathways were antigen processing and presentation (P = 8.40 × 10−5), measles (P = 3.30 × 10−3), and cell adhesion molecules (CAMs) (P = 5.66 × 10−3) (Table 4).
Conversely, in 199 upregulated genes (Additional file 1: Table S8), the most significant GO terms were noncoding RNA processing, ribosome biogenesis, rRNA processing, ribonucleoprotein complex biogenesis, and rRNA metabolic process (Additional file 1: Tables S15, S16), and 45 genes were related to translation, transcription, DNA replication and repair, and protein and RNA degradations.
