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Interestingly, the two film scene labels with the most significant linkage to chemicals measured were "suspense" and "comedy".
The most significant linkage signals found in the complete set of families were observed across a broad, 37 cM interval on 4q13-25, with LOD scores ranging from 2.02 to 2.62, increasing to 4.50 in families with older average age at diagnosis.
Microsatellite INRA004 shows the most significant linkage with the rex phenotype among the 359 rabbits (LOD = 78; ⊖ = 0).
However, the most significant linkage was found for male normal weight gallstone carriers (p = 0.01410, OR = 6.85), indicating that the occurrence of the rs9514089 polymorphism is gender- and weight-specific.
The most significant linkage was recorded for each permutation round.
The most significant linkage was between marker FCA700 and Tabby (Z = 7.56, θ = 0.03).
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A plot of pairwise linkage disequilibrium values log(p) against R showed that the most significant linkages between a reference SNP and its linked SNP occurred for R > 0.8 (Additional file 1: Figure S1).
A decreasing LOD (Log10 of the odd ratio) score approach (from 6 to 3, step = 1) was used to reveal the most significant linkages (LOD = 6) to the weakest linkages (LOD = 3) and was used to group linked markers in LGs.
The most statistically significant linkage results were with markers on chromosome 4 (LO D = 3.166 and NPL = 3.65 with rs 875864, 4p16.1, 8.38 cM).
The most significant evidence for linkage was observed at ∼60 cM on chromosome 17, with 95 families showing some evidence of linkage (non-parametric linkage score >0 at 60.1 cM on chromosome 17, which is the linkage peak from our first genome-wide scan (GWS) (Lange et al, 2003)).
Day 4 was marked by the most significant increase of linkage from transcription factors altered on day 4 towards others altered later.
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