The most significant, however, has to be the timeline.
It is the interior design that is most significant, however.
Most significant, however, was the Golf, initially called the Rabbit in the United States, which was introduced in 1974.
Perhaps most significant, however, is change from within: a new generation of gay men, lesbians, bisexuals and transgenders who see the world, and themselves, quite differently.
Most significant, however, was the impact of Einstein, as well as that of the three great mathematical logicians of the late-19th and early-20th centuries the groundbreaking German Gottlob Frege and the authors of the monumental Principia Mathematica (1910 13), Russell and Alfred North Whitehead.
Arguably it was the third wicket which was the most significant, however, as indecision resulted in youngster Ross Taylor being sacrificed by Fleming, who had nudged the ball into the off-side and dallied while Vaughan swooped to relay to Flintoff.
Our most significant findings, however, still explain less than 5% of the variance in HDL-C level, a trait that is up to 70% heritable.
The most significant advance, however, lies in video on demand.
Its most significant figure, however, lived in North Africa.
The most significant power, however, is the potential ability to control the team's front office.
The most significant uncertainty, however, is how much carbon humanity will choose to put into the atmosphere in the future.
