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One of the most significant genetic variations that has been identified in association with panic disorder is mutation of a gene designated HTR2A (5-hydroxytryptamine receptor 2A).
After identifying rice chromosome 5 as the location of the most significant genetic factor for floury endosperm characteristics, 14 additional SSR markers were further incorporated into the linkage map skeleton to increase marker density (see Table 4; Locus, Ap = 2, 3).
The ε4 isoform of the APOE gene is the most significant genetic risk factor for AD [7].
In this study, the most significant genetic association was seen with the CHEK2 I157T allele.
The most significant genetic signatures emerging from gene-chip analysis were confirmed and validated by qPCR.
The APOE4 allele, found in 15% of the population, remains the most significant genetic risk factor for LOAD [ 13].
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The ε4 allele is the risk allele and is the most significant known genetic risk factor for LOAD.
To determine the most significant predicted genetic interactions with tau, all genes with P < 0.05 from all 35 networks were compiled together.
All 35 network profiles were then cross-referenced to one another in order to determine the most significant predicted genetic interactions with tau (see Materials and Methods for criteria of network inclusion).
The most significant ones are genetic engineering, media and environmental condition's optimization.
The most significant advantage of genetic faecal analysis is that dietary samples can be collected with virtually no disturbance to the birds.
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