Sentence examples for most significant domain from inspiring English sources

Anecdotally speaking, for cases where the total FPR of the most significant domain hit is below this range, the specific function may be inferred from this significant hit.

Also, the stratification of the quantified hits via the ordered total FPR measures hints at the amount or level of function transfer from the most significant domain hit to the sequence.

At the same time, the stratification of the quantified domain hits (via the ordered total FPR) helps to guide the amount or level of function transfer from the most significant domain hit to the sequence.

In addition, the stratification of the quantified domain hits (via the ordered total FPR) helps to guide the amount or level of function transfer from the most significant domain hit to the sequence, depending on the magnitude of the total FPR.

And given the lack of function annotation from the most significant domain DUF819 (albeit having a total FPR = 0.0), the closest functional postulation for Q9K8K1_BACHD was proposed by the next most fold-critical significant MFS_1 domain (total FPR = 0.0) with a representative PDB structure 2CFP|A that describes a 12-TM lactose/H+ symporter.

After filtering for domains with at least 10-TM, there remains 8 domain hits (out of which, 6 have representative PDB structures) on top of the most significant DUF819 domain hit, as listed in Table  4.

In order to select the most significant interacting domain patterns, χ2 statistics is calculated for each pattern.

Since the CSIDOP method only keeps the most significant interacting domain patterns from the closely related protein interaction pairs across species, PPI pairs in the test dataset not containing the patterns in the lookup table will result in no prediction.

Most of the overlap occurred between panels within the same domain, but among the most significant cross-domain connections was the overlap of the "Synthetic Chemistry and Materials" panel with the "Molecular and Structural Biology and Biochemistry" panel.

Interestingly, the rate of erroneously assigned genes presents the most significant correlation with domain complexity, suggesting that protein families with multiple protein domains "attract" non-orthologous proteins due to domain sharing.

The p-value for the most significant gene, MACRO domain containing 2 antisense RNA 1 (MACROD2-AS1), passed the multiple testing threshold of 2.93 × 10− 6 for testing 17,016 genes.