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Liesl Schillinger misses the most significant defect of Brian C. Anderson's "South Park Conservatives: The Revolt Against Liberal Media Bias" (June 26).
And what's the most significant "defect" you detect in your organization?
Readers: What's the most significant "defect" that's inspiring you to grow as a professional?
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Thereafter, more attention is drawn on voids and dry spots since they are known to be the most significant defects in RTM PMCs.
As shown in Figure 6A and Table 1, although there was a variation, Class I swi3 mutants (swi3-NBT7 and E40) had the most significant defects in Cds1 activation, which is consistent with the results of PFGE after HU treatment (Figure 5B).
The most significant defects of UBR2 mice show spermatocytes without complete synaptonemal complex.
The H4-R36 and H3-L61 residues appear to be particularly important in controlling Spt16 interactions with transcribed genes since specific amino acid substitutions at these location H4-R36A and H3-L61W cause the most significant defects in the distribution of Spt16 across transcribed genes.
However, the most significant defects in endocytosis were seen with the three siRNAs targeting stonin 2. Synapses depleted of stonin 2 showed a substantial slowing of synaptic vesicle retrieval (T1/e prolonged by 2.5-, 2-, or 2.2-fold compared to control, Figure 1B).
The most significant challenge in design defect management is to identify design activities that are likely to cause defects.
Most significant is that pyridinic defects are relatively readily incorporated at low nitrogen doping levels while at nitrogen content higher than 5% the major incorporation mechanism is dominated by pyridinic and pyrrolic defects on an equal basis.
The most significant limiting factor for nerve defect regeneration is the gap length which has to be bridged.
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