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Translation initiation and protein folding are the two most significant cellular process networks.
The most significant cellular target of UV is DNA.
These agree well with the most significant cellular component found, which "cytosolic large ribosomal subunit" is (1.05E-46).
An overall view of the most significant cellular functional categories predicted [ 80] to be affected by this pool of Rasless miRNAs is represented in Figure 6C.
The earliest and most significant cellular degeneration process begins with the chloroplast, which contains most of the proteins in a leaf cell.
In an excellent review by Amaral et al. [ 19], the authors demonstrated that the pathways involved in metabolism and energy production have been recognized as the most significant cellular pathway in the human spermatozoa.
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An Ingenuity analysis of these top 500 genes revealed the following most significant categories: Cellular Compromise (8.5 × 10-5 – 2.8 × 10-2) and Post-Translational Modification (9.8 × 10-5 – 5.0 × 10-2).
Within the lungs, the pool of inflammatory phagocytes is the most significant and important cellular ROS generating system [ 42]; metals and organic substances adsorbed on PM surface have been related to their phagocytic oxidative burst [ 42].
The 5 most significant molecular and cellular functions identified were cellular development, cellular growth and proliferation, cellular function and maintenance, cell death, and lipid metabolism [Additional file 7].
According to the core analysis of all CP genes (n = 322) using the IPA, the most significant top 5 cellular functions were cellular development, gene expression, cellular growth and proliferation, cell signaling and cell morphology (Table 4).
Our results focused on genes which play a significant role in the most important cellular processes and demonstrated a large difference in their expression patterns between BC and control samples.
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