Sentence examples for most significant binding from inspiring English sources

Among them, the hydrogen bond between the side chain carboxylate group of Glu478 and one of the hydroxyl groups of the inhibitor is found to be the most significant binding force stabilizing the inhibitor in the active site.

C. jejuni 11168-GS and 11168-O bound terminal Gal structures independent of linkage and the nature of the sub-terminal carbohydrate, with the most significant binding observed at growth conditions that mimic those of the potential hosts.

However, the two modifications, particularly mstA37, provide the most significant binding energies.

For example, this feature allows the user to quickly browse among regions of ChIP enrichment above a user-specified threshold value to rapidly visualize the most significant binding regions.

The most significant binding peaks (FDR ≤ 0.05), which coincided in both replicates, were analyzed by the program RSAT dyad-analysis to predict binding sequence from all peak genomic binding sites [ 36].

The most significant enriched binding site in the upstream regulatory region of genes which were expressed at higher levels in T2DM patients versus MetS was HIF1 (p = 1.25 × 10−12, Table  5A).

After conducting structural alignments of the individual components of our system HLA-B*57 01 HLA-B*57 01nding peptide bindingbacavir, and co-binding pockete), we concluded that the most significant differences bounden binding pocket, abacavir, and peptide occurred from the peptide amino acid sequence [44].

The most significant reductions in binding occurred for the Grb2, Grap2, Vav2, and Vav1 SH2 domains.

The most significant recovery of binding was observed with cold oligonucleotides mutated for Sp1 (lane 4), AP-1 (lane 5), and CREB (lanes 9 and 10).

The most significant reduction in binding to the CD44 peptide was observed for the alanine mutant Arg716, which comprised a residue change located in the Ex subdomain and is facing towards the same molecular surface as that used for PI binding of the PH subdomain, that is, the proposed molecular surface facing plasma membranes.

Remarkably, among the ChIP signal sites, the over-representation was the most significant for PPARγ-binding sites (Fig. S4), and not observed for H3K4me3- and H3K27me3-binding sites (Fig. 5B D).