Sentence examples for most severe variant from inspiring English sources

The most severe variant was the nucleotide change c.673C>T in XRCC4.

Most patients had STEMI, the most severe form of AMI.

In addition to the lognormal OR coefficient and modeled OR at the most severe sequence variant grade, Table  6 also reports the OR point estimate at the most severe sequence variant grade.

EBS with pyloric atresia (EBS-PA) is one of the most severe EBS variants.

Given that the most severe Hb variants occur in the β chain, the low abundance of these ions could be a problem.

The World Health Organization (WHO) recommendation to do so with eight weekly doses of 45 mg primaquine base does not come with evidence of safety among the most severe G6PD deficiency variants, which happen to be most common where P. vivax occurs in greatest abundance (south and southeast Asia).

It was shown that the naive approach, which estimates the minor allele frequency by the fraction of observed minor alleles in the reads, can significantly over-estimate the true minor allele frequency, and that the effect is most severe for rare variants.

The most severe consequence for each variant was reported and compared to the ANNOVAR results.

ANNOVAR reports the most severe consequence for a variant across all transcripts present at that position in the genome, so with more transcripts available when using ENSEMBL there is an elevated chance of finding a more severe consequence for one of the ENSEMBL transcripts.

The location and the effect of the eSNPs were assigned using the Variant Effect Predictor [ 43] with the SScrofa10.2.74 assembly, where the results were restricted to the most severe annotation of the SNP variant.

In the comparison of annotation tools here, we restricted each tool to report just the most severe consequence annotation for each variant, to avoid comparisons becoming too unwieldy.