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For simplicity, the clinical manifestations of pneumococcal disease are modeled as mutually exclusive, with risk of occurrence following a hierarchy of severity from most severe to least severe: meningitis, bacteremia, pneumonia, AOM.
Scores were assigned to each patient on a scale from 0 to 3 (0 for the absence of the symptom, 3 for the most severe) to evaluate the severity of 4 typical sIBM symptoms: protein aggregation, inflammation, necrosis, fibrosis (Table S1).
All 17 officers received disciplinary letters, which varied in seriousness from reprimands, the most severe, to letters of admonishment, memorandums of concern and letters of counsel.
There are three sport classes for visual impairment: LTA-VI B1, B2 and B3: Rowers in this sport class have varying degrees of visual impairment, with B1 being the most severe To ensure that races are fair, rowers compete only against those in the same sport class.
Items are scored from 1 (most severe) to 7 (no impairment) [ 40, 41].
One intervention option for management of the most severe to profound hearing loss in older adults is cochlear implantation.
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Steam + 5% acetic acid pretreatment was found to cause the most severe changes to the EFBF surface.
All these reforms were to be achieved amidst the most severe cuts to the health budget.
Fire is one of the most severe conditions to which steel structures may be subjected to.
"Perhaps the most severe blow to public trust was the revelation that there were scores of too-big-to-fail institutions operating at the heart of finance.
The unrest poses the most severe test to date of the peace treaty signed in 2006.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com