Documented cases also probably represent the most severe or symptomatic cases, although most cases are unrecognized, and self-resolution is the norm.
In its most severe form, major symptomatic pulmonary emboli may lead to cardiovascular compromise and even death.
Although it is clear that most severe disease occurs during primary infantile infection, symptomatic upper respiratory tract infections occur throughout life.
Although most hyponatremic patients may appear to be asymptomatic, severe symptomatic hyponatremia is a medical emergency that calls for immediate treatment.
When symptomatic, neuroschistosomiasis (NS) is the most severe presentation of schistosome infection; cerebral invasion is mostly caused by S. japonicum, with spinal cord involvement due mainly to S. mansoni or S. haematobium [ 7].
Children who have severe, symptomatic epilepsy are those who are most commonly prescribed rescue medication [6].
Conversely, the delayed inflammatory response, observed among symptomatic subjects, is at the basis of the most severe hemorrhagic symptoms of EVD [ 19].
The PCS levels in the most severely affected patients in these studies were comparable to those reported in previous studies of patients with severe symptomatic gout and patients with gout who had not responded to urate-lowering therapy [ 20, 35].
Most participants were recruited from an existing population-based cohort of individuals with at least moderately severe symptomatic hip or knee OA residing in two counties of Ontario, Canada.
25 26 In AS, most publications on LV geometry have been based on studies in small groups of patients with severe, symptomatic AS, where up to 90% prevalence of concentric LV hypertrophy has been reported.
