Sentence examples for most severe reduction from inspiring English sources
The average fracture toughness reduction for this zone is 27%, with the most severe reduction being 42%.
EMMAX method had the most severe reduction in the number of significant effects, and the PCA method using 20 principal components and GLS had similar significance levels.
The most severe reduction occurred in E2F genes with a single remaining repressive E2F, in contrast to several repressive and activating E2Fs in mammals and zebrafish (Zhu et al., 2013, Dev Biol).
MALAT1_C KO cells, with the greatest loss of MALAT1 expression (Fig. 6c), show the most severe reduction in proliferation, with approximately half the cellular population at 72 h compared to the control clone (pDECKO-GFP).
Immunohistochemical staining for collagen type II content indicate collagen was not affected by treatment, however duration in culture had a significant impact with day 32 samples having the most severe reduction compared to all other treatment groups (p = 0.0460).
Within the DN stages, the most severe reduction in total numbers was consistently detectable in the DN2 subset (average ~55-fold reduction) and the DN3 subset (average ~25-fold reduction), whereas DN1 and DN4 fractions were relatively increased – indicating a partial block at the DN1 DN2/3 transition in Mysm1−/− thymi.
The cuts would be the largest since John B. Mattingly became commissioner of the agency in 2004, and among the most severe reductions since it was created as a stand-alone department in 1996.
Big metropolitan areas, where levels of need and deprivation are highest, will proportionally face the most severe reductions in funding.
Spleens, thymuses, and livers showed the most severe reductions of ACDase activities in Asah1P361R/P361R animals.
Type 1 fimbriae-deficient strains showed most severe biofilm reduction among mutants investigated, which may reflect their importance in the irreversible attachment of cells to the surface.
Donald Trump elicits the most severe reaction.
