Sentence examples for most severe phenotypes from inspiring English sources

However, mutations in Pex3, Pex16, and Pex19 result in the complete absence of peroxisomes and are coupled to the most severe phenotypes (Steinberg et al., 2012).

Among overexpressing lines, the ten plants with the most severe phenotypes did not develop any crown roots, but the radicles and lateral roots appeared normal.

Patients with the shortest telomeres exhibit the most severe phenotypes [24].

The myosin point mutation of Arg403 to glutamine (R403Q) causes one of the most severe phenotypes of FHC.

We tested all 12 lines by expressing them in the developing wing, thorax, and eye (Fig. 1C,G,K) and selected the line that produced the most severe phenotypes.

Interestingly, the most severe phenotypes, including death at 3 months of age, were observed in the mixed 129/Sv-CD-1 129/Sv-CD-1 129/Sv-CD-1 existence of importanimalsindicatingeles in the outbrexistencetrain.

The magnitude of the most severe phenotype (−2.3 standard deviations) is based on observed relative testis weights in the most severely affected males.

The most severe phenotype appeared in the first weeks and months of life and presented with hypoketotic hypoglycemia, hypertrophic cardiomyopathy, and encephalopathy.

It is possible that the manifestation of the most severe phenotype is due to an unlikely combination of genetic and non-genetic factors (endogenous or environmental factors, which may be precipitating or modifying the phenotype).

However, in certain families with motor aura, such as this one, it is possible that the most severe phenotype is caused by an unlikely combination of polygenic traits and non-genetic factors.

Cryopyrin-associated periodic syndrome (CAPS) is a group of rare autoinflammatory diseases, and of these, chronic infantile neurologic, cutaneous, and articular/neonatal-onset multisystem inflammatory disease (CINCA/NOMID) syndrome has the most severe phenotype.