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Death is the most severe outcome of disease or injury and is thus of fundamental significance to health surveillance.
For the analysis on patient record level, patients with more than one AE during admission, the AE with the most severe outcome was used for further analysis.
AS is the most relevant subtype for all patients with predominantly spinal symptoms and is regarded together with PsA as the SpA with the most severe outcome.
The most severe outcome is fetal alcohol syndrome (FAS), which can manifest variably with diverse combinations of craniofacial, growth, central nervous system (CNS), and neurobehavioral abnormalities (Jones et al. 1973; Sampson et al. 1997).
Although S. japonicum produces similar lesions like S. mansoni, the fibrotic lesions and hepatosplenomegaly, the most severe outcome of schistosomiasis, is relatively more frequent and severe in S. japonicum[ 44].
This spectrum includes: FAS, the most severe outcome of alcohol exposure in utero; Partial FAS; and Alcohol Related Neurodevelopmental Disorder (ARND), the diagnosis of which requires confirmation of maternal alcohol exposure and neurodevelopmental problems not otherwise explained.
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Indeed, of the 11 patients with the most severe outcomes, including two deaths, 10 were not wearing a helmet.
These facts would have made her message all the more sobering and given her another chance to use her life to point out the most severe outcomes of premature parenthood.
But it's still important to get the vaccine because it can reduce some of the most severe outcomes of the illness, according to a 2017 report from the CDC.
Peripheral arterial disease, leading to ischemia or lower limb hypoperfusion is associated with the most severe outcomes, including lower probability of healing, longer healing times, higher probability of ulcer recurrence, greater risk of amputations, and potentially higher mortality [ 4].
Furthermore, our patients with culture-confirmed bacterial meningitis represented pathogens with the most severe outcomes (streptococci and staphylococci) whereas we had no cases of meningitis caused by N. meningitidis which otherwise represent an infection with a fairly good prognosis [ 16, 28, 29].
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