Sentence examples for most severe end from inspiring English sources

We also need to know more about how different levels of PD severity can affect treatment outcome, e.g. whether patients in the most severe end of the severity spectrum will profit from more or less intensive treatment or psychosocial support.

Growing evidence suggests SAD simply reflects the most severe end of a spectrum of social anxiety severity (Crome et al., 2010; Stein and Stein, 2008), and it is possible people experiencing anxiety only in public performance situations experience sub-threshold social anxiety not severe enough to meet diagnostic criteria.

The five 'non-compliance' issues it found were classed as "minor" – one in category A and four in category B (with category D being at the most severe end of the suffering scale).

We hypothesized that although perineal urethrocervicoplasty can be a successful first-line procedure in patients with normal bladder, a more radical reconstruction was necessary to achieve continence in cases lying at the most severe end of the spectrum.

Multiorgan dysfunction syndrome (MODS), the most severe end of the spectrum of sepsis syndrome, may involve the myocardium [2,3], and this has clear prognostic implications, with some reports pointing to a direct correlation between the onset of myocardial dysfunction and mortality in septic shock [4].

Therefore, patients attending Patan Hospital may only represent the most severe end of the spectrum of enteric fever as many patients may seek local advice or self-treat.

This recession, which officially began in December 2007, now appears virtually certain to be the longest downturn -- and possibly most severe -- since the end of World War II.

This recession, which officially began in December 2007, now appears virtually certain to be the longest downturn — and possibly most severe — since the end of World War II, as evidenced last week by a demoralizing rat-a-tat of grim reports on jobs, sales and public confidence.

Obviously, the color code bias problem is most severe near the end of sequencing.

Families depending on monthly income often have a cyclic pattern of food restrictions, with food shortages most severe at the end of the month when household resources are depleted [ 12, 27, 28].

BERLIN — Just hours after one of Europe's most severe political impasses ended Sunday, a new deadlock already had emerged.