Sentence examples for most severe difficulties from inspiring English sources

He and his colleagues must overcome the most severe difficulties in the coming year.

Possibly, those facing the most severe difficulties were the likeliest to answer, and some respondents probably wished to paint a grim picture, to help convince lawmakers and policy makers to take action.

However, post-hoc analysis demonstrated a significant benefit in the quartile of patients with the most severe oxygenation difficulties.

Royal Doulton is in the most serious difficulties.

For the most prevalent areas of severe difficulties, infrequency still enjoyed a high percentage (14.4%).

The difficulty is most severe when the child in question is two years old.

It is also more likely that patients with the most severe disability experience the most difficulty accessing primary care, yet this would not be recorded if they did not respond.

For symptom severity, the four most severe symptoms (i.e., problems with sexual interest, hair loss, constipation, difficulty sleeping) were the same for both age groups.

Symptoms of the most severe fourth stage include dementia, aggression and difficulty finding words.

The committee welcomed the concentration on fragile states, which are generally the most poverty-stricken, but warned it would lead to "severe difficulties in ensuring every pound is well spent in war-torn environments with corrupt and incompetent governments".

For most of this year, UNICEF and its partners have faced severe difficulties in reaching hundreds of thousands of children in Aleppo, Rural Damascus, major parts of Homs, Deir ez Zour and Rural Dara'a.