Sentence examples for most severe defect from inspiring English sources

The severity of the lesion for each child was defined by the most severe defect on the affected tooth/teeth.

The most severe defect, aphakia, was accompanied by an aberrant infolding of the retina.

There is widespread deficiency of GCase activity and protein levels in PD+GBA brains, with the most severe defect located in the SN (58%) and putamen (48%).

The most severe defect was observed in cardiac muscle where ATGL deficiency led to massive TG accumulation, mitochondrial dysfunction, and cardiomyopathy causing premature death 3 4 months after birth.

One of the most severe defects in continuous casting products is concerned with the cracks provoked by improper design of the spray cooling system.

Regarding the novel disease phenotypes in neural cells, we observed that mutations of XPA in patients lead to the most severe defects in NER, compared to the cells with other XP mutations.

One of the most severe defects that can be prevented is neural tube defects (NTDs).

Interestingly, the most severe defects were observed with the H84A variant.

The most severe defects, present in a small number of embryos, were neural tube defects including anencephaly, microcephaly and exencephaly.

We observed the most severe defects in the proximal gonad, with multiple small, membrane-bound compartments often visible near the most mature oocytes.

DKO mice presented with the most severe defects, resulting in a malformed mandible lacking the normal curvature seen in control embryos.