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At the most severe concentration tested (0.5M for cations paired with chloride and 1.0M for cations paired with sulfate), glucose consumption rate decreased between 12% (K2SO4) and 33% (Na2SO4) as compared to the control.
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The effect of simmondsin on meal patterns (decreased meal size, meal duration and eating rate, increased latency to eat) is most severe at the highest concentration.
These goals become difficult to achieve in case of BSI due to multi-drug resistant pathogens with high MICs to antimicrobials, in the most severe patients where low antibiotic concentrations are common, and when the source control is incomplete or impossible.
Sedimentation and flow-induced migration of particles can produce concentration gradients that are most severe near boundaries.
Although the serum level of SCF in healthy controls and patients with non- severe asthma was similar, the most severe patients had significantly higher serum SCF concentration in comparison both to healthy control and non-severe asthmatics.
Some colic horses showed extremely high plasma lactate concentrations before surgery, the most severely ill horses usually having the most severe changes.
Patients with acute respiratory distress syndrome (ARDS), the most severe form of ALI, present with elevated plasma concentrations of oleic acid (OA), which is one of the most abundantly occurring fatty acids in human plasma [ 2].
The effect is most severe at lower doses, according to new research, including concentrations similar to what might be found in the environment.
This concentration was chosen for comparison to the most severe exocyst mutants, as its effect on growth rate was similar to untreated sec8-3 and exo84b-1 lines.
A score calculated by the triage nurse, based on mottling and capillary lactate concentration, appears to be useful for identifying the most severe patients.
Increased CSF levels were detected in term neonates with perinatal asphyxia and the highest concentrations were found among neonates with the most severe HIE [ 43].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com