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However, the recruitment approach used in this study may have resulted in unintentional exclusion of those with the most severe AT as these athletes may not have been able to compete at the events where recruitment took place.
In the current experiments the mdx mouse pathology is most severe at the 4 week time point, while the Sgcg−/− mice are most severely affected at 12 weeks.
The stress is most severe at the high end of the market.
There are four Class A avalanche zones — the most severe — at nearby skiing areas, and numerous backcountry locations for study.
The destruction was most severe at a plant in Miyagi Prefecture that makes Blu-ray discs and magnetic tapes.
But the problem is most severe at Hanford, a 560-square-mile tract in south-central Washington that was taken over by the federal government as part of the Manhattan Project.
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And this often means only the most severe or at-risk cases get seen.
The Indiana-Maryland tussle for the championship Monday night at the Georgia Dome is Indiana's final and most severe test at dictating tempo.
Human rights groups have said that Palestinians and Israelis have both singled out civilians for attacks, but the groups have directed their most severe criticism at Israel.
Some of the schools are overcrowded, with the most severe problem at Colonia Middle School, where the average class size is 26, compared with a state average of 21.
By the end of the night one asylum seeker was dead, another shot, another in a critical condition, and dozens injured after the most severe disturbance at the controversial centre since it reopened in October 2012.
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