Sentence examples for most serious drawback from inspiring English sources
The most serious drawback to the drug is its addictiveness.
The risk of cardiotoxicity is the most serious drawback to the clinical usefulness of anthracycline antineoplastic antibiotics, which include doxorubicin (adriamycin), daunorubicin or epirubicin.
A simple method for the filter design is presented which is aimed at overcoming the most serious drawback of advanced filtering algorithms for high dimensional systems related to very high computational cost in evaluation of the filter gain.
Unfortunately, he dismisses what, from the standpoint of reducing total health-care expenditures, is the single most serious drawback to such an approach; namely, the probability that effectively case-managed patients will survive longer than they would without intensive ambulatory care and will thereby offset their reduced frequency of hospitalization with an increase in their time at risk.
Up to now, of course, the most serious drawback of the whole Left Wing philosophy has been its lack of the lighthearted carnality of capitalistic enterprises, typified for us by the bosomy girls we see at Republican rallies or leading American Legion bands.
The most serious drawback of SVD precoding is the requirement of complete CSI at both the transmitter and receiver.
One of the most serious drawbacks of barrier screws is that they are more susceptible to solid bed plugging; severe plugging results in process instabilities (surging).
This caused an unequal age distribution in the different groups and was therefore potentially one of the most serious drawbacks of this study.
Nevertheless, one of the most serious drawbacks upon using hydrocarbon-rich fuel gas is the deposition of carbon or carbon filament formation on the electrode, blocking gas diffusion at the catalytically active triple phase boundary anode/electrolyte/fuel by coking, and in parallel inducing mechanical damage via carbon filament formation and nickel "dusting".
Storing face images (or corresponding feature vectors) in the database in plain form is the most serious security drawback of this system.
Most have serious drawbacks.
