Sentence examples for most serious difficulty from inspiring English sources

The interface presenting the most serious difficulty was of an information nature.

But British banks and financial institutions, whose bosses plunged in with excessive enthusiasm, ended up in the most serious difficulty when trying to make themselves global players.

The most serious difficulty facing Darwin's evolutionary theory was the lack of an adequate theory of inheritance that would account for the preservation through the generations of the variations on which natural selection was supposed to act.

The issue, named by Wallace 2003 as the "incoherence" probability problem, is arguably the most serious difficulty.

The most serious difficulty with an HMM model is overfitting, which means that it represents the training sequences well but fails to generalise to related sequences not present in the training set.

The most serious difficulty with the ribozyme world scenario is ecological in nature: different replicators occupying the same habitat and replicating with different rates will compete for the (common) resources of their replication.

Royal Doulton is in the most serious difficulties.

Of them all, Serbia is facing the most serious difficulties.

This is why we must raise the level of funding we make available to the International Monetary Fund so that it can aid those countries facing the most serious difficulties.

Arguably, the most serious difficulties for Anomalous Monism are not with its adequacy but with its justification.

Broadening of the present program with additional examples of good practice and solutions, particularly for domains where the most serious difficulties during implementation occur (such is application of restitution, for example).