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Not surprisingly, the genus Symbiodinium showed the most sequence variation within species.
Among the three genes, most sequence variation was observed in the rpoB gene.
Multi-species comparisons of the predicted protein sequences revealed that the defining architectural features of Ush1g in placental mammals (i.e., three ankyrin domains and a SAM domain) are highly conserved in the three fish Ush1g paralogs, with most sequence variation residing within the central region of the protein of unknown function (additional file 12).
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Most sequence variations correlated to subspecies pedigrees (japonica vs. indica), so we focused on mutations that putatively cause major effect functional changes.
Most sequence variations observed in the NGS reads by indexed amplicon sequencing reflect mutations well in the library in comparison with the HRM analysis data.
SNPs are the most common sequence variation among plants and are often functionally important.
SNPs are the most common sequence variation in the human genome and can affect coding sequences, splicing, or transcription regulation.
The most common sequence variation occurring in the human genome is the stable substitution of a single nucleotide, also known as single nucleotide polymorphisms (SNPs).
The most common sequence variation in the human genome is the stable substitution of a single base, the single-nucleotide polymorphism (SNP).
Based on our Vero cells passages and human-to-Vero transition data, we estimated that, at most, one sequence variation from the original tissue virus can be accounted for by in vitro culture artifacts.
However, the actual region seems to be well conserved in most sequences, the variation is mainly with respect to the specific residues found at each position.
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