As with primary peristalsis, LES relaxation is also the most sensitive component of secondary peristalsis.
Of all the amide bands of the peptide group, amide I has proven to be the most sensitive probe of protein secondary structure.
It also raises another question: for all the apparent superiority of i-CDK9 to older drugs (lower IC50, fewer and less sensitive secondary targets), most of the results presented here could have (or have) been obtained with flavopiridol at similar doses.
In order to determine a time-frame during which posterior secondary cells are most sensitive to N-signalling, we maintained Nts-1 pupae at 30°C for at least 1 hour prior to the experiment to create an "N-off" condition.
The deletion strain of Mft1, a subunit of the THO nuclear complex, was identified as the most sensitive strain to nickel in our secondary validation screen and the deletion strain of Hpr1 was identified as the sixteenth most sensitive strain (Additional file 2).
For assessing secondaries, Ga PET/CT is the most sensitive modality.
In our secondary analyses, the cost-effectiveness values were most sensitive to a lowering of the projected long-term survival benefits of t-PA and to moderate or greater increases in the projected medical costs for patients in the t-PA group after the first year.
One-way sensitivity analyses showed incremental costs to be most sensitive to polypill adherence, discount rate and revascularisation costs, while incremental QALYs and ICERs were most sensitive to utility values of patients on secondary prevention and patients having had a second MI.
Inhibition by H2S affects both hydrogenation and direct sulfur extraction HDS routes, but, secondary hydrogenation of desulfurized aromatic products was found to be the most sensitive to inhibition.
However, a secondary objective of our analysis is to identify the threshold which is most sensitive to declining functional health, reflecting the current stage of development of multi-morbidity.
