Of all the amide bands of the peptide group, amide I has proven to be the most sensitive probe of protein secondary structure.
The limit of detection (3σ/slope) of our probe was 61 nM, which make our probe one of the most sensitive fluorescent probes for H2O2 detection.
Indeed, the electrical transport measurement is one of the most sensitive techniques for probing defects in single nanoscale structures [17 19].
Sometimes the PCR is not sensitive enough to detect the causing agent in clinical situations with expected low viral load or limited amount of sample, even if every measure has been taken to design the most sensitive primers and probe from the sequence known about a specific virus.
The most sensitive process able to probe the Majorana nature of neutrinos and discover Lepton Number Violation is the neutrino-less double beta decay.
The accuracy of true positive detection of in silico modeled changes of 1.5-, 2-, and 4-fold was reduced for RNA samples with RIN values ≤ 7. The effect was greatest for probe sets most sensitive to sample integrity and was less pronounced for probe sets unselected for an effect of RNA degradation on signal level.
We aim to determine which commercially available NIRS probe represents the most sensitive layout of sources/detectors for the greatest sensitivity in observing tissue oxygenation at the optimal depth for TBI.
"He has probed the most sensitive nerve in US-China relations – the territorial integrity of the motherland and the idea of the inevitable return of Taiwan to the motherland's embrace".
Furthermore, the (Z -4,4′-(((1,2-diphenylethene-1,2-diyl) bis(4,1-phenylene))bis (oxy))bis(butan-1-aminium) (Z -4,4′- was the most sensitive and chosen as the probe for Hep detection.
Samples with RNA integrity numbers less than or equal to 7 showed a significant increase in false positives relative to undegraded liver RNA and a reduction in the detection of true positives among probe sets most sensitive to sample integrity for in silico modeled changes of 1.5-, 2-, and 4-fold.
