Sentence examples for most robustly replicated from inspiring English sources

The FTO gene is the first and most robustly replicated gene that is related to body weight and fat mass [ 32, 33].

As described by several authors, the OS5 rSNP3383 SNP is still the most robustly replicated polymorphism associated with OA and the only locus successfully validated across diverse Asian and European populations.

A naturally occurring sequence variation (rs738409) resulting in a isoleucine (I) to methionine (M) substitution at position 148 (I148M) (18) of the protein is the most robustly replicated genetic variant associated with liver damage (19), hepatic neutral fat retention (17) and progression to chronic liver disease (20– 20).

First, we randomly divided our original population into two groups, a "training set" and a "test set" and showed that the model was robustly replicated in both subsets without loss of power or sensitivity (Table 4).

First, such an approach requires the existence of genetic variants that have been shown to be robustly (replicated in several independent studies) associated with the non-genetic modifiable exposure of interest.

Genetic association studies have recently revealed nearly 40 robustly replicated loci for type 2 diabetes [ 2].

However, these results have yet to be robustly replicated in larger cohorts.

To date, robustly replicated findings of CNVs associated with type 2 diabetes have not been reported.

Despite its substantial heritability, no robustly replicated genetic risk loci had been found until recently.

Robustly replicated genetic variants associated with LUTS would provide useful information in assessing both prognosis and potentially treatment response.

This is the first robustly replicated common susceptibility locus found to be associated with metformin treatment response.