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To identify the loci most robustly associated with invasive disease, we utilized 3 distinct, commonly applied statistical approaches to identify those gene loci (from each of the three statistical approaches and across the 2 series) that overlapped in differentiating invasive and non-invasive disease.
Of the 3 candidate genes, TGFBR1 was the most robustly associated with LV function.
The two genes most robustly associated with CD (NOD2 and IL23R) are not part of the selected module.
Seizure event was most robustly associated with the WISC processing speed score (R = 0.505, F1,16 = 16.310, P = 0.001).
Intron 2 SNP, rs2834213 was most robustly associated with TB, but its biological importance is currently unclear.
This study has identified genes and gene expression modules that, based upon currently available data, are most robustly associated with CR and/or aging in the laboratory mouse.
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In ATHENA, the prognostic factors most closely and robustly associated with worse OS were: liver metastases or ⩾3 metastatic organs; disease-free interval (DFI) ⩽24 months; prior anthracycline and/or taxane therapy; and triple-negative breast cancer (TNBC).
Most notably, the distance between the IG and every other landmark was robustly associated with X count after FDR.
Recent genome-wide association (GWA) studies have identified multiple loci robustly associated with BMI and risk of obesity.
The FTO signal was robustly associated with BMI and osteoarthritis, and showed evidence of association in the replication osteoarthritis dataset.
Similarly, while low eGFR was robustly associated with all-cause mortality, only eGFRcys showed significant association with cardiovascular mortality.
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most robustly replicated
most robustly identified
most robustly studied
most robustly represented
most robustly recapitulated
most robustly supported
most robustly expressed
most robustly attested
most robustly reduced
most robustly activated
most robustly detected
most robustly labeled
most robustly altered
most robustly related
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Justyna Jupowicz-Kozak
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