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The metabolite set for amino acids was most robustly altered, showing a decline in response to DR in every tissue and at every age.
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Direct contrast of DNQX and muscimol effects confirmed that muscimol robustly altered hedonic reactions while DNQX did not (muscimol versus DNQX, site X drug interaction, 15 minutes, F 1,21) = 6.296, p = .020; 1 hr, F 1,21) = 6.957, p = .015).015
This identified 25 probesets consisting of 22 genes consistently and robustly altered by loss of CoVa expression.
Preliminary results have identified several gene-coexpression networks that are robustly altered by ethanol in a tightly coordinated fashion (Wolen et al., in press).
We chose to study examples of these indicator proteins in mouse models of Batten disease so as to undertake 'hypothesis-driven' research specifically focused on proteins known to be robustly altered when axons and synapses change their vulnerability status (29– 31).
The improvement in simple motor speed/ attention following ATD is in keeping with the ascribed role of 5-HT in the cortex, however performance on tests of executive function is not robustly altered.
These results validate our methodology and support that, although JAK2 and JAK3 show 70% identity between their crystal structures, these differences are sufficient to robustly alter peptide preference [31], [32].
White matter and grey matter alterations were most robustly co-localized in the right anterior temporal lobe including the most consistently involved white matter tract, the uncinate fasciculus.
You can't even say that the brilliant Willis Burks II and Stephen McKinley Henderson are outstanding, because the nine-member cast gives you ensemble acting at its most robustly realistic.
"I did watch, and occasionally unscrewed a spark plug," he recalled, but the expertise he developed most robustly was "ferrying in cherry Cokes from the nearby restaurant".
The results show that the proposed approach performs most robustly in comparison with the others.
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CEO of Professional Science Editing for Scientists @ prosciediting.com