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Comparison between the outcomes from the two models and their underlying wind datasets (Comparison of model outputs) allowed us to evaluate the effect of different models and model input data on hazard analyses and therefore to highlight the most robust outcomes of the assessment.
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The most robust outcome measure we found was emergency admissions for different conditions calculated using Hospital Episode Statistics data.
Since the composite scores are considered as the most robust outcome measurement for the SF-36, we have focused on them in our comparisons.
Clearly, mortality is the most robust outcome but large numbers of patients are required to be maintained within a trial for long periods.
We elected not to study the outcome of ventilator associated pneumonia as we consider mortality to be the most robust outcome, and this was the focus of recent large trials of selective digestive decontamination.
Our data suggest that a greater degree of desaturation occurs during a 6MWT regardless of the physiological load imposed by the test, and this may be the most robust outcome of the 6MWT.
Although in general in metastatic disease ORR is not considered to be the most robust outcome measure, in advanced esophagogastric cancer, ORR may be a clinically relevant end point, given the high symptom burden that patients may suffer from that may be alleviated by response to treatment [ 1].
The most robust result was for naproxen sodium 550 mg.
EvaGreen gave most robust result and lowest failure rate [ 37].
Compared to the PFIT-s the FSS-ICU was the most robust functional outcome measure in the ICU setting.
Although CVD mortality is clearly the most robust clinical outcome, cardiovascular morbidity is likely to be at least as relevant to patients, providers of healthcare, policy makers and insurance companies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com