The impact of sample collection variation on these candidate markers was tested in the subset of samples with higher SMV scores so that the most robust markers could be used to create disease classifiers.
The conventional end point of neoadjuvant CT studies in breast cancer is pathological complete response (pCR), representing the most robust surrogate marker of longer-term outcome (Fisher et al, 1997, 1998; van der Hage et al, 2001; Heys et al, 2002; Bear et al, 2006; Mieog et al, 2007).
In this study of the watermelon genome, we identified the most robust skeletal markers with strong linkages and high confidence levels.
The reported inconsistencies in the effects of the diagnostic DNA markers for the proposed favourable alleles of lcyE and crtRB1 require further investigation of these markers using diverse inbred lines to identify the most robust and effective markers for marker assisted selection.
The major finding of the study is that serum levels of calprotectin appeared to be the most robust and reliable marker of treatment response in both axial and peripheral SpA, even outperforming hs-CRP in some analyses.
Informatics analysis of such data is still in its infancy, but on-going improvements to assembly and identification will allow simple selection of the most robust and informative markers from any species into a working assay, thereby enhancing the development of marker-assisted breeding strategies.
The startle response is one of the most robust PTSD disease markers to date.
Analysis of SRAP markers indicated that these were the most robust relative to other markers, detecting more maternal- and paternal-specific markers per informative primer.
Serum HGF increases after ficlatuzumab administration makes HGF the most robust and convenient pharmacodynamic marker for ficlatuzumab treatment.
The intensity of the startle response, a motor reflex, is probably the most robust potential PTSD disease marker to date.
