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Among these, four common issues prevail: i) identifying the most robust controls and the ethics of sham (or 'placebo') surgery, ii) achieving large enough sample sizes to be meaningful, iii) using patient important outcomes in lieu of 'convenient' outcomes, and iv) managing the inherent differential expertise biases that exist in all surgical trials.
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The neurocontroller design uses the dual heuristic programming (DHP) algorithm, which provides the most robust control capability among the adaptive critic designs (ACDs) family.
Most robust control techniques start with a computationally intensive initialisation method which has to be repeated each time the model changes.
The neurocontroller design uses the novel optimization neuro-dynamic programming algorithm based on dual heuristic programming (DHP), which has the most robust control capability among the adaptive critic designs family.
Where biological efficacy is uncertain, the most robust control remains a placebo [ 43].
Despite having by far the most robust privacy controls on the web, some early fiascos and the complexity of those controls still make people feel uneasy.
He went on to say that the "Saudi authorities have their own procedures for investigations" and "the UK operates one of the most robust arms control regimes in the world".
"And if not, will you commit to immediately carrying out an inquiry into this issue?" UKTI said: "We take arms export responsibilities very seriously and aim to operate one of the most robust export control systems in the world.
From a screen of 11 candidate housekeeping genes, the human β2-microglobulin (B2M) and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) genes were empirically determined by us to be the most robust endogenous control genes for human kidney tissue and human cell lines, respectively (data not shown).
Associations of endotoxin with the inflammation score and copper with the coagulation score were the strongest and most robust to control for study site.
Since by computing stochastic optimal controls, random parameter variations are incorporated into the optimal control design, most insensitive or robust controls are obtained.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com