Sentence examples for most resistance mutations from inspiring English sources

Indeed, most resistance mutations described are a one-base-pair change that modifies the binding site of the pesticide in the corresponding neuroreceptor, which is likely to be costly, as other molecules also bind to that site [2].

Using meta-analysis, we have found that most resistance mutations in bacteria confer a fitness cost.

Most resistance mutations are unique to a particular species and drug.

Conversely, the frequency of most resistance mutations in HCV-1b infected patients was high at both time points.

Examining the impact of resistance mutations across a range of bacterial species and antibiotics, Melnyk et al. (2015) find that although mutations with little to no cost exist, most resistance mutations are in fact costly.

The distribution of the most common resistance mutations in the RT was as follows; M41L (8.5%) and T215Y (8.5%) and K70R (4.8%).

The PCR was designed to amplify a fragment covering the protease and the first half of the reverse transcriptase (RT), which harbour most known resistance mutations to licensed antiretroviral drugs.

T215 revertant substitutions were by far the most prevalent resistance mutations (3.8%) in the study population (figure 3).

Most baseline resistance mutations were lost in subject 7 during treatment interruption becoming undetectable even by deep sequencing at the time of virological failure.

Most additional resistance mutations leading to changes in susceptibility predictions were found after virological failure to deep salvage therapy (Table S1).

The most common resistance mutations which would lead to decreased efficacy of Atripla are M184V/I (leading to emtricitabine resistance), K103N (efavirenz resistance), and K65R (tenofovir resistance).