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However residential aged care was not the focus for this review and most reported trials were single-disease based.
Feedback interventions are much less resource intensive, and therefore potentially more scalable and feasible to use in everyday practice, but most reported trials have uncertain or high risk of bias, 33 and there is little evidence for their use in improving safety outcomes.
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This was also true of the most recently reported trial (CREATE; [ 11]).
However, when engaged with the counselling process within the trial, most reported being relieved to have someone to talk to in confidence.
Seventeen of these 23 cohorts were part of randomised controlled trials, and most reported mid-term follow-up.
Detailed reporting of the method of measuring faecal and blood radioactivity was uncommon, and although most reported at least a reference four trials had neither details nor reference.
24 Most trials reported complete outcome data: two trials insufficiently reported on recruitment, attrition, and exclusion to permit judgment.
25 Most trials reported some assessment of pain (general or specific to the neck) (15 trials), and range of movement (ROM) (13 trials).
Most trials reported of a positive outcome of either opioid reduction or pain score improvement, and publication bias (skewed publication of only trials with a positive outcome) cannot be ruled out.
Most trials reported separately on anti-nausea and anti-vomiting data.
Most trials reported length of hospital stay after randomisation as a mean or median value without standard deviations.
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CEO of Professional Science Editing for Scientists @ prosciediting.com