First, although it was not surprising that we found a lower osmolal gap after the infusion of HS than mannitol, the most reliable formulas for serum osmolality estimation was identified in present study.
Among the above mentioned tumor makers, serum CA19-9 is the most reliable biomarker of ovarian mature cystic teratomas; higher levels of serum CA19-9 are correlated with larger tumor sizes.
In a literature review, Han et al. [ 11] reported that a high serum viral load is the most reliable indicator of viral replication in predicting development of HCC (serum viral load of ≥10 copies/mL for HCC occurrence and 10 copies/mL for a poor prognosis).
Prospective studies have linked serum ferritin, the most reliable marker of body iron stores, and dietary heme iron intake to incident T2DM (5– 7).
As discussed above, the UMDES study appears to provide the most reliable data set for characterizing current serum concentrations in young adults because of the very low LODs attained in that study.
Using data from the cases in the nested case-control study to assess the predictive ability of the models, we confirmed that the most reliable predictors of DDE were age and serum cholesterol, and the most important predictors of PCBs were age, serum cholesterol, and residence in the Midwest or Northeast.
The examination of paired serum samples remains the most reliable serodiagnostic procedure for dengue.
11 Yet, the detection of islet autoantibodies in serum is currently the most reliable diagnostic test for type 1a (autoimmune) diabetes in subjects with hyperglycemia.
To guide the treatment of iron-deficiency anemia in pregnancy, the haemoglobin concentration is the most used test in spite of its low accuracy, and serum ferritin is the most reliable test, although its cutoff point remains an issue.
The most reliable predictor of poor prognosis was a serum bilirubin of over 50, which was associated with a median survival of 0.6 months with no patient surviving more than 1.57 months,.
