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However, the benefit of antireflux therapy for chronic cough remains unclear, with most relevant trials reporting negative findings.
The most relevant trials for the UK are the comparisons of GemCis/GemCarbo to MIC/MVP.
The first was published in 2000 and is clearly outdated since it was issued before the appearance of all recent and most relevant trials [ 38].
Although tranexamic acid (TA) has been effective in reducing bleeding after cardiac surgery, the TA dosing scheme varies extremely and the agent is highly overdosed in most relevant trials.
We cannot rule out that we have missed relevant trials because we limited our search to the Cochrane Library and MEDLINE, but the most relevant trials are likely to have been identified by our searches.
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A glance to some possible drug combinations will also be provided, along with an update of the most relevant ongoing trials.
One recommendation would enable patients from all communities to access and share clinical and molecular data about their cancer and to be matched with the most appropriate medicines or, where necessary, to enroll in the most relevant clinical trials.
Most of the relevant trials recruited hospitalized patients from different populations, especially the noncritically ill patient groups (Table 2).
The most relevant randomized controlled trials of interferon-alpha (IFN) for naïve patients with chronic hepatitis C (CHC) published in a decade, just before appearance of pegylated IFN trials in 2000, were included in this paper.
This section describes the adjuvants that have been employed during the clinical development of diverse malaria vaccine candidates, considering the most relevant vaccines and clinical trials.
We then describe the most relevant image-guided radiotherapy trials, identify the main bottlenecks and their potential solutions, and end with short-term perspectives.
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